- a clear substance naturally produced by the body
- retains water and keeps skin moist
Hyaluronic acid (HA) is mainly found in our skin, connective tissue and eyes. It has been shown to help lubricate the joints and hydrate the skin, providing a plump and youthful appearance by binding and retaining water molecules. 1
Hyaluronic acid is a key molecule in various anti-aging formulas, as it is important in skin cell metabolism. The ability to keep the skin environment humid, along with stimulating growth factors, promotes wound healing and tissue regeneration. 2 Hyaluronic acid is also able to reduce skin inflammation, for greater skin health. 3
A clinical study focused on ingestion of hyaluronic acid showed that it moisturizes the skin and is expected to improve the quality of life for people who suffer from dry skin. HA is reported to be absorbed by the body distributed, in part, to the skin. 4
Another study on 60 patients that were administered oral intake of HA at a rate of 120 mg/day showed that skin luster and suppleness significantly improved after 12 weeks. The group that was taking HA showed significantly diminished wrinkles compared with the placebo group. The results suggest that oral HA inhibits skin wrinkles and improves skin condition.5
- Papakonstantinou, E., Roth, M., & Karakiulakis, G. (2012). Hyaluronic acid: A key molecule in skin aging. Dermato-endocrinology, 4(3), 253-258.
- Keen, M. A. (2017). Hyaluronic Acid in Dermatology. Skinmed, 15(6):441-448.
- Chen, L. H., Xue, J. F., Zheng, Z. Y., Shuhaidi, M., Thu, H. E., Hussain, Z. (2018). Hyaluronic acid, an efficient biomacromolecule for treatment of inflammatory skin and joint diseases: A review of recent developments and critical appraisal of preclinical and clinical investigations. International Journal of Biological Macromolecules, 116:572-584.
- Kawada, Chinatsu & Yoshida, Takushi & Yoshida, Hideto & Matsuoka, Ryosuke & Sakamoto, Wakako & Odanaka, Wataru & Sato, Toshihide & Yamasaki, Takeshi & Kanemitsu, Tomoyuki & Masuda, Yasunobu & Urushibata, Osamu. (2014). Ingested hyaluronan moisturizes dry skin. Nutrition journal. 13. 70. 10.1186/1475-2891-13-70.
- Oe, Mariko & Sakai, Seigo & Yoshida, Hideto & Okado, Nao & Kaneda, Haruna & Masuda, Yasunobu & Urushibata, Osamu. (2017). Oral hyaluronan relieves wrinkles: A double-blinded, placebo-controlled study over a 12-week period. Clinical, Cosmetic and Investigational Dermatology. Volume 10. 267-273. 10.2147/CCID.S141845.